Services & Facilities

IGSB features state-of-the-art core technologies at the University of Chicago and Argonne National Laboratory. These facilities support efforts to define the complex genetics underlying disease and the development of potential therapeutics to target disease pathways.

Current IGSB Core Facilities include:

Advance Imaging Core (AIC)

  • Zeiss Lightsheeet.Z1 Digital Selective Plane Illumination Microscopy (SPIM) System 
  • Super resolution in 3 colors and in 3 dimensions by single molecule localization using Ground State Depletion (Leica SR GSD 3D)
  • Access to advanced fluorescence microscopes and confocal systems (BSD Integrated Light Microscopy Core)
  • Advanced image analyses and expertise

Genome Engineering Core (GEC)

  • Protein tags (GFP, etc) for imaging, ChIP-Chip, ChIP-seq, or in situ hybridization
  • Custom modifications of BACs including deletions, insertions, substitutions.
  • CRISPR (fly, human cell line)

Celluar Screening Center (CSC)

  • High-throughput screening of small molecule and whole genome siRNA libraries
  • Assay development and optimization into 96, 384, or 1536 well micro titer plates including high content screening

Micro-Western Array Core (MWAC)

  • High-throughput quantification of abundance and modification of pre-selected protein targets


Any questions regarding the Institute’s facilities should be addressed to Shelly Wright, IGSB Research Director email: mhwright@uchicago.edu (773) 834-0583.



Marc