Sam worked to create the CSC and has been the Technical Director since its inception in 2006. With over twelve years of high-throughput screening experience in both industry and academia Sam provides project management and high-level support to the group.
Also, Sam is responsible for overseeing the Microwestern Array Core and leading projects through the workflow. He brings over twelve years of automation and assay development training and over eight years of directorship of the Cellular Screening Center in the Institute for Genomics and Systems Biology.
David Blair was an MSTP student in the Andrey Rzhetsky Laboratory. He is currently finishing the M.D. side of his M.D./Ph.D. program.
Dr. Borevitz is interested in the genetics of adaptation to seasonal light environments. Quantitative and population genetic approaches in Arabidopsis thaliana are used in his lab to dissect local and regional phenotypic variation.
Mimi conducts the assay development and runs the Microwestern Arrays in the core. She is also responsible for all of the daily operations of the Microwestern Array Core.
Assistant Investigator, Institute of Cellular and System Medicine, National Health Research Institutes
Senior Software Researcher for Pingar Ltd.
Conducts screens and maintains equipment in the Cellular Screening Center
Liza Holtzman was the IGSB Business Administrator and is responsible for administrative functions in the IGSB.
Dr. Jones was jointly appointed Assistant Professor of the IGSB and the Ben May Institute for Cancer Research in September 2006. As a postdoc at Harvard, Jones pioneered the use of protein microarrays to study complex molecular signaling networks involved in human cancers and other diseases. Dr. Jones left the IGSB in 2013 to become Vice President of VMRD, Inc. in Pullman, Wa.
Lead technician on a project that uses BAC-recombineering to systematically epitope-tag all human transcription factors.
Dr. Kumar’s laboratory is interested in the cellular and molecular biology of murine natural killer (NK) cells. These cells are believed to act as the first line of defense against tumors and viral infections. In addition they secrete a variety of cytokines including 1FN-g and GM-CSF that can influence the inflammatory response. Two aspects of NK cell biology are of particular interest to us: the development of NK cells from multipotent progenitor cells, and the identification of NK cell receptors and their ligands.
We are a mammalian biology lab interested in two major research topics: Genetic Basis of Human Brain Evolution & Stem Cell Biology. Our other research interests include neurogenetics, bioinformatics, and developing technologies for high-throughput functional genomics.
Our lab primary interest is to understand the connection between genetic factors and human psychiatric disorders or behaviors. Current research project is the genetic studies of bipolar disease (BD) using molecular genetics, genomics and bioinformatics approaches.
Professor in Beijing Institute of Genomics, Chinese Academy of Sciences
My research group tackles the following questions. What is the nature and extent of genetic variation within and between human populations? What are the biological and evolutionary processes that have produced the observed patterns of variation? How do genotypes contribute to phenotypes for complex traits (and how can we identify the relevant genetic variants)?
Our interest is in understanding how different evolutionary forces have shaped patterns of genetic variation in humans, and conversely, in learning about recombination, demography and selection from patterns of genetic variation observed in samples of extant humans. Our research combines modeling, the development of statistical tools and data analysis. The lab is “dry”, although we often collaborate closely with experimentalists.
Nicole conducts high-throughput screens, cell culture, and performs all details of lab management in the CSC.
As IGSB Research Manager, Jay Rehm oversaw a variety of scientific projects including the genome-wide mapping of human transcription factor binding sites under the auspices of the NIH ENCODE Project and its sister project, modENCODE, which focuses similar attention on the transcription factors of model organisms. Jay Rehm coordinated numerous scientific collaborations between IGSB and other research groups, administered the Chicago Center for Systems Biology (CCSB), and managed the IGSB core facilities.
Dr. Janet Rowley, MD, was the Blum Riese Distinguished Service Professor of Medicine, Molecular Genetics & Cell Biology and Human Genetics at the University of Chicago. She was internationally renowned for her work in the discovery of molecular genetic alterations found in human malignancies, Rowley studied chromosome abnormalities in leukemia and lymphoma to provide critical scientific insights that have led to cures for previously untreatable cancers. Her discoveries resulted in more accurate diagnostic techniques and the development of effective treatment protocols targeted to particular patient subgroups. Among her numerous honors, Rowley was awarded the 2009 Presidential Medal of Freedom, the 1998 Albert Lasker Clinical Research Award, the 1998 National Medal of Science, the 1989 Charles S. Mott Prize from General Motors Cancer Research Foundation, and the AACR’s G.H.A. Clowes Memorial Award in 1989 and the Dorothy P. Landon-AACR Prize for Translational Cancer Research in 2005. She was a member of numerous honorary societies including the National Academy of Sciences, the Institute of Medicine, the American Philosophical Society and the American Academy of Arts and Sciences.
Assistant Professor, Bose Institute, Kolkata
Alumni - White lab
Fellow in Cheng Li’s lab at the Dana Farber Cancer Institute
Julia Woods was the IGSB Project Assistant from 2012-2013. She left the IGSB for a position at the University of Chicago Divinity School.
Shelly Wright, Director of Research & Operations for the Institute for Genomics & Systems Biology, works with faculty and administrative leaders in the planning, initiation, and management of complex research initiatives across all areas of the IGSB. Her responsibilities include overseeing all areas of IGSB operations.
Assistant Professor at University of North Carolina
His main interests were cloud computing, biomedical text mining, multiple kernel learning methods, data integration and fusion.
He worked with Andrey Rzhetsky and Robert Grossman.
He also collaborated with computatioal biologist at K.U.Leuven, my Alma Mater, on disease gene prioritization. He was the developer of MerKator, a kernel based platform for cross-species computational disease gene prioritization.